Norwich (9th SPS) Symposium (BIO-PPS-2007)

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GENERAL
INFORMATION

SCIENTIFIC
PROGRAM

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ABSTRACTS

DELEGATE
REGISTRATION

YOUNG SCIENTIST
MINISYMPOSIUM

SATELLITE
SYMPOSIUM

New Millennium Biomedical Symposium & Exhibition Series
British International Open Peptide & Protein Symposium: BIO-PPS-2007

9th International Symposium

SOLID PHASE SYNTHESIS

COMPLEMENTARY SOLUTION METHODS
& COMBINATORIAL LIBRARIES

Biologically and Biomedically Active Peptides,
Peptidomimetics, Proteins, Oligonucleotides, DNA, RNA, PNA, etc.
Small Molecule Chemical Diversity, Drug Design, etc

Dates: 28th August to 1st September, 2007
Venue: U.E.A., NORWICH, England, UK

*Co-Chairmen:*
Prof Roger Epton (Wolverhampton, UK)	&	Dr Ram P Sharma (Southampton, UK)

Organised Under the Auspices of the European Peptide Society
& RSC (UK) Protein and Peptide Science Group

GENERAL INFORMATION

The City of Norwich and the University of East Anglia

Norwich Castle

Norwich Castle Interior

Riverside Quarter

Norfolk Broadlands Scene

The Historic City of Norwich dates back over two thousand years. By the late Middle Ages it had become the largest walled city in England outside of the London. Today it is still dominated by its massive Norman Castle and Cathedral and has more Medieval Churches than any other city in Western Europe. It has a wealth of old Merchants' Houses, Halls, Museums and Taverns, as well as magnificent modern facilities such as the New City Forum and the nightlife of the Riverside Quarter. Its huge Six Day Market was founded at the time of the Norman Conquest and has been held regularly on the same site ever since. As the capital heart of rural East Anglia, Norwich is a splendid tourist centre and the gateway to the acclaimed Norfolk Broadlands National Park.

The University of East Anglia by Norwich, provides an excellent venue for the Symposium and Symposium Exhibition. Basic University rooms are pleasant and modern (see 'Residential University Accomodation' below for more details). Although the Symposium is designed to be fully residential participants are free to pay the registration fee only and to make Hotel or Guest House accommodation arrangements in Norwich, if they so wish.There are extensive sports and leisure facilities, including an olympic size swimming pool. The University boasts the world renowned Sainsbury Centre for Visual Arts and is within easy access of the City with its opportunities for entertainment and sightseeing.

International Travel to Norwich and the University Campus is conveniently via the budget (cheap flight) Airport, London Stansted, coincidentally the nearest major airport to Norwich. A regular Jetlink Coach Service goes direct from London Stansted Airport to the University Campus. Another convenient air travel option is to fly to Amsterdam and then onward by KLM Royal Dutch Airlines to arrive directly at the local Norwich Airport and take the short taxi ride to the University. For delegates who have no option but to travel via central London there is a regular direct rail link from London Liverpool Street Rail Station to Norwich.

The Symposium Lectures, Poster Sessions, Symposium Exhibition and Satellite Symposium will comprise a fully integrated event on the University Campus. There will be free time for informal discussion, for sight-seeing and for social activities. There will be the option of an afternoon Symposium Trip. There is no formal accompanying person's programme but delegate's guests and partners will find in the old City many relaxed opportunities for leisure and tourism.

Early Arrival/ Late Departure is a possible option. Participants may stay at the University, on a room and breakfast basis, over the weekends before and/or after the Symposium for the purpose of leisure and tourism and/or to take advantage of discount airfares.

Norwich Cathedral

Market and Medieval Guildhall

A Norwich Tavern

Pull's Ferry and Watergate

SCIENTIFIC PROGRAMME

Symposium Objectives

To provide a forum for the presentation of advances in solid phase synthesis and combinatorial chemistry as well as in complementary solution phase methods and other non-classical technologies.

To promote the potential of the methods and the compounds synthesized for the solution of problems in the biological and biomedical sciences, including drug discovery, optimization and development.

Biological targets will include peptides, glycopeptides, proteins, oligonucleotides, DNA, RNA, etc.

Non-natural targets will include mimetics and analogues of all kinds, including diverse small organic molecules.

Symposium Lecture Programme

The detailed Symposium Lecture Programme is under development. The developing programme will be finalised in the weeks immediately prior to the Symposium. It will include Keynote, Invited and Contributed Lectures. Some of these may be grouped in parallel sessions.

Click Here to View Some Confirmed Lecture Titles

Distinguished Speakers

Prof F. Albericio (Barcelona, Spain)
Prof B. Austen (London, UK)
Prof S. Brocchini (London, UK)
Prof D. Graham (Glasgow, UK)
Prof A. Eberle (Basel, Switzerland)
Dr R. Frank (B'schweig, Germany)
Dr A. Friedler (Jerusalem, Israel)
Dr M. Gait (Cambridge, UK)
Prof F. Hudecz (Budapest, Hungary)

Prof U. Langel (Stockholm, Sweden)
Prof R. Leatherbarrow (London, UK)
Prof K. Nokihara (Kyoto, Japan)
Dr W. Rapp (Tubingen, Germany)
Dr R. Vinayak (Mountain View, CA, USA)
Prof J. Wade (Melbourne, Australia)
Dr D. Wellings (Runcorn, UK)
Dr P. White (Nottingham, UK)
Prof Dr K-H. Wiesmuller (Tubingen, Germany)

Topics and Themes for Short Lecture and Poster Abstract Submission

The following list is for guidance only. Contributed lectures, oral and poster abstracts on other topics, in harmony with those listed, are welcome.

Solid Phase Synthesis of peptides, polypeptides, glycopeptides, lipopeptides, oligosaccharides, DNA, RNA, genes and proteins; peptide nucleic acids, PNA, chimera and other hybrids, small organic molecules, mimetics of all kinds; Combination of solid phase, enzymic and recombinant DNA-based methods; purification, analysis and characterization of target molecules and intermediates by HPLC, ion exchange, capillary electrophoresis, etc.
Multiple and Combinatorial Synthesis in solid phase and solid phase / solution synthesis leading to peptide, oligonucleotide and non-natural small molecule organic chemical libraries. Microwave-assisted synthesis. Application in the generation of bio-active species, e.g. drug lead discovery and optimization, enzyme substrate mapping; Bio-active sequence location, e.g. epitope mapping, sequencing by hybridisation.
Chemical Advances and Methodology including resin developments, scavenger resins, protection and deprotection strategies; main chain and side chain protecting groups; coupling methods; monitoring methods; target molecule detachment; segment synthesis and segment condensation; microwave-assisted synthesis, rapid and large scale synthesis, etc.
Computer Applications in solid phase and combinatorial chemistry; target modelling and computer-aided design; modelling of supports and intermediate assemblies.
Automated Synthesis and Instrumental Analysis including commercial synthesizers, commercial sequencers, mass spectrometry and other methods.
Drug Discovery, Development and Delivery - including small molecule organics, nucleic acids and PNA, antisense strategies; drug design for efficient delivery, etc.
Peptide, Protein and Nucleic Acid Antibody and Vaccine Strategies - Peptide epitopes and other immunogens; diagnostic and other applications of peptide/ glycopeptide/ nucleotide antibodies, etc.

Abstract Submission Deadlines - Late Abstracts

Contributed (Longer Lecture) Paper Abstracts - June 15th, 2007.

Oral (Short Lecture) Communication Abstracts - June 29th, 2007
Note that a limited number of reserve slots will be left for Late-breaking Oral Communications.
Contact Symposium Organiser, Prof Roger Epton, r.epton@mayflower.demon.co.uk for details.

Posters Abstracts - July 6th, 2007
Note that a few Late Poster Abstracts can be accepted after the deadline right up to the first day of the Symposium. However, Late Poster Abstracts missing the deadline cannot be guaranteed to be included in the Participant Abstract Book (Bioorganic and Biomedical Symposium Preprints 2007) to be distributed to delegates on arrival at the Symposium.

Abstract Preparation and Abstract Submission

ABSTRACT PREPARATION: Abstracts should be prepared in draft as follows. Type 12 characters to inch. Use 10pt font size and single space throughout. Use CAPITALS for PAPER TITLE. Author's names (put asterisk * before presenter's name), address and zip code, in capitals and lower case. Begin headings from left hand margin. Optimum dimensions of the abstract, including title, authors names and affiliation(s), are about 18cm width x 15cm height approx. (270 sq cm area of text) printed out on A4 paper.

ABSTRACT SUBMISSION: Please E-mail the Abstract, as a MS Word attachment,together with a copy of the Registration Form/ Provisional Registration Form or a Registration Reference Number to Prof. Roger Epton - E-mail: r.epton@mayflower.demon.co.uk

(Note: Abstract transmission by MS Word E-mail attachment is essential to facilitate text transcription for printing of the Participant Abstract Book. Simple plain text E-mail transmission is not recommended because features of the text can be irrevocably lost.

ACCEPTANCE OF ABSTRACTS: Abstract acceptance for lecture, short lecture or poster presentation will be decided on the grounds of intrinsic merit and relevance to the main scientific coverage of the Symposium. The last named criterion will be less rigidly applied for posters.

Young Scientist Minisymposium & Poster Competition Awards

Predoctoral Students and Postdoctoral Researchers (up to 30 years of age) submitting short oral or poster abstracts are eligible to compete for these awards. Competitors will be invited in advance to give a 15-20 min oral presentation in a "Young Scientist Minisymposium Session". There will be a separate award for Best Young Scientist Poster. The awards will be graded on both scientific content and presentation. The value of the awards will range from £GBP 100 to £GBP 250. Young Scientists wishing to be considered for these competitive awards must indicate this at the time of abstract submission and supply a statement from their supervisor confirming that they are the principal investigator involved in the work.

REGISTRATION & ROOM BOOKING

Registration Matters

The Delegate Registration Fee includes attendance at all Scientific Sessions and the Symposium Exhibition, Copy of the Abstract Book (Bioorganic & Biomedical Symposium Preprints 2007) the Welcome Reception, and Morning/Afternoon Refreshments and Mid-day Lunches on Wed 29/ Thur 30/ Fri 31 August.

The Delegate Registration Fee entitles delegates to attend lecture sessions interchangeably at both the Symposium and its concurrent Satellite Symposium. Fee catagories are as follows:-

	Delegate Concessionary Registration Fee (£GBP 255) (University/ Hospital/ Public Sector Delegates, etc. up to 27th July)

	Delegate Full Registration Fee (£GBP 345) (All Industry Based Delegates up to 14th August) (All Other Delegates from 28th July up to 14th August)

	Pre-Doctoral Full-time Student Registration Fee (£GBP 120) (Up to 27th July) (Confirmatory note from Supervisor on Student's Institution Letterhead needed).

	Accompanying Person's (Non-scientific) Registration Fee (£GBP 20) (Up to 14th August) (Attending Welcome Reception & Tea/Coffee Intervals but not Lunches, not Scientific Lectures, and not attending in order to gain Scientific/Technical Information/Benefit from the Symposium Exhibition).

Click Here to Register On-line

University Rooms/ Room Booking

University Single Rooms are pleasant and modern. Each room has its own private shower and toilet. University Rooms are only available through direct booking with the University (UEA Conferences Norwich).

Delegate Room Bookings may be made on either a "Room/ Breakfast Only" basis or an "Evening Meals/ Room/ Breakfast" (i.e. "Half-board") basis. The Half-board option is available only for the Core Nights (e.g. for Tue 28, Wed 29, Thu 30 or for Tue 28, Wed 29, Thu 30, Fri 31) of the Symposium. Delegates are free to put together and book their own University Room/ Evening Meal Combinations.

Examples of Delegate University Single Room plus Evening Meals (if any) Combinations, together with Charges incurred for the whole Symposium are as follows:-

Example 1.

Standard Four Night "Half-board" Stay (Recommended Option) (£GBP 282.30)
(Includes all Evening Meals & Banquet/ Room/ Breakfasts, etc.)

That is for the four (core) nights of the symposium:-

1.	Evening Dinner Tue 28 / Room Night Tue 28 / Breakfast Wed 29 August - (£GBP 62.10)
2.	Evening Dinner Wed 29 / Room Night Wed 29 / Breakfast Thu 30 August - (£GBP 62.10)
3.	Evening Dinner Thu 30 / Room Night Thu 30 / Breakfast Fri 31 August - (£GBP 62.10)
4.	Evening Symposium Awards Banquet Fri 31 / Room Night Fri 31 August / Breakfast Sat 01 September - (£GBP 96.00)

Example 2.

Abbreviated Three Night "Half-board" Stay (£GBP 186.30)
(Includes all Evening Meals/ Room/ Breakfasts, etc.)

This option is available for participant room bookings for the first three (core) nights of the symposium only and does not include Symposium Banquet. That is for:-

1.	Evening Dinner Tue 28 / Room Night Tue 28 / Breakfast Wed 29 August - (£GBP 62.10)
2.	Evening Dinner Wed 29 / Room Night Wed 29 / Breakfast Thu 30 August - (£GBP 62.10)
3.	Evening Dinner Thu 30 / Room Night Thu 30 / Breakfast Fri 31 August - (£GBP 62.10)

Example 3.

Economy Room & Breakfast Only Four Night Stay (£GBP 192)
(Economy "Room/ Breakfasts Only" options do not include Evening Meals)

1.	Room Night Tue 28 / Breakfast Wed 29 August - (£GBP 48.00)
2.	Room Night Wed 29 / Breakfast Thu 30 August - (£GBP 48.00)
3.	Room Night Thu 30 / Breakfast Fri 31 August - (£GBP 48.00)
4.	Room Night Fri 31 August / Breakfast Sat 01 September - (£GBP 48.00)

Example 4.

Abbreviated Economy Room & Breakfast Only Three Night Stay (£GBP 144)
(Economy "Room/ Breakfasts Only" options donot include Evening Meals)

1.	Room Night Tue 28 / Breakfast Wed 29 August - (£GBP 48.00)
2.	Room Night Wed 29 / Breakfast Thu 30 August - (£GBP 48.00)
3.	Room Night Thu 30 / Breakfast Fri 31 August - (£GBP 48.00)


NOTE:	Early Arrivals/ Late Departures (£GBP 48.00 per night) *(Room occupancy outside of the core nights is available on a "Room/ Breakfast Only" basis)*

	This facility is for the benefit of delegates staying at the University who wish to arrive early/ depart late in order to connect with international air flights or to extend their stay for the purpose of leisure and tourism. There are no on-campus evening meal facilities outside of the core nights

Click Here to Book University Room On-line

Local Norwich Hotels / Other Accommodation

The Norwich Symposium is designed to be fully residential on the University Campus. However, participants are free to pay the Symposium Registration Fee only and to stay independently in a Hotel or other accommodation if they so wish. Inevitably, a Hotel Single Room Option will be more expensive than either a University Single Room/Breakfast Package or an Evening Dinner/Single Room/Breakfast ("half-board") Package available on Campus.

A Number of Visitors to the University opt to stay at the Holiday Inn, Ipswich Road, Norwich - Tel: +44 (0)870 4009060 -, a short taxi ride away from the University.

Important Note: Hotel Rooms and University Rooms cannot be booked by the Symposium Secretariat. University Rooms can only be booked via the University (UEA Conferences Norwich).

- SYMPOSIUM VISIT -

Sandringham House & Royal Estate

(Afternoon - Thursday 30th August)

Sandringham House together with the Sandringham Royal Estate, is the private residence and retreat of Her Majesty Queen Elizabeth II. It is first and foremost a country home and, as a place for informal relaxation, is held in much affection by The British Royal Family. As a visitor venue, Sandringham provides an insight into the interests, personal achievements and collections of four generations of British monarchs, King Edward VII, King George V, King George VI and the present Queen, Elizabeth II. Sandringham House is unique in that its interior has a discreet magnificence while yet retaining a homely ambience and welcoming atmosphere. The small but intensely beautiful Church of St Mary Magdelene is situated on the Royal Estate and it is here that The Queen and her family gather to worship at Christmas. It is from Sandringham that The Queen most often broadcasts her Christmas message to Britain and The British Commonwealth.
Sandringham House is set among sixty acres of beautiful mature gardens. These have developed from the original formal planting and tranquil lakes conceived by King Edward VII with successive monarchs contributing to create the splendid mature all-year-round landscaped gardens enjoyed today.

The Symposium Visit will take place on Thursday 30th August. Buses from the University for Sandringham at 12.00h approx. The visit is scheduled to include Sandringham Church, highlights of Sandringham House Gardens, the Museum and a Tour of Sandringham House.

For more information about Sandringham visit:-
The Sandringham Estate Official Web Site

Sandringham House

Sandringham House Gardens

LEISURE & TOURISM

Daytime Activities

Accompanying Persons not attending lectures and delegates arriving early/ departing late will find a wealth of attractions both in Norwich and in the Norfolk area. There is no formal Accompanying Person's Programme. However, the compact nature of the City offers easy opportunity and scope for individual tourism.

Norwich as a Heritage City In addition to the Norman Castle and the Cathedral, there are numerous other historic buildings to explore. Medieval features include some thirty two churches, the Guildhall and merchant houses such as Dragon Hall and Strangers' Hall. The landmark New City Forum - a dynamic centre for information, learning and entertainment - houses 'Origins' - an unmissable state-of-the-art visitor attraction devoted to Norfolk's history and that of its famous people such as Elizabeth Fry and Admiral Lord Nelson.

Shopping in Norwich In addition to its unique historic open-air market, Norwich has a wide variety of captivating specialist shops. These are variously located in the Royal Arcade, Timberhill, Ber Street and elsewhere and are complemented by Castle Mall an exciting futuristic shopping complex with a huge glass gallery looking out on the castle. Norwich is designated as one of the top ten shopping destinations in the UK.

Norwich Castle was built by the Normans over 900 years ago, As in the case of the Cathedral, it was built with Caen stone brought by sea from Normandy. Originally a Royal Palace and one of the outstanding secular buildings in Europe, in the 14th century it became the City prison, a role it was to fulfil for the next 600 years. From 1894, Norwich Castle became the City Museum and Art Gallery. Today, the dramatic interior of the Castle Keep provides a backdrop for displays of Norwich Silver, Arms and Civic Regalia. Video and computer animation depict Castle life in the time of the Normans and there is a dedicated display devoted to the history of the Castle as a prison. Visitors can take guided tours of both the dungeons and of the battlements with spectacular views over Norwich

Norwich Cathedral - one of the finest complete Romanesque buildings in Europe - was begun by Bishop Herbert de Losinga in 1096 and finally consecrated in 1278. The building is mainly of Caen stone. This was brought from Normandy, at great hazard and expense, by ship up the English Channel and then by barge up the River Wensum to the ancient City Watergate close-by Pull's Ferry. The Cathedral was magnificently and sensitively enhanced throughout the Middle Ages, this time with English stone from Northamptonshire.
Among the historic medieval artefacts which adorn the Cathedral, are over a thousand intricately carved and painted stone roof bosses. These illustrate the whole Bible story. The number and variety of these fine art treasures greatly exceeds those in any other Cathedral worldwide.

Norfolk and The Norfolk Broadlands. Norwich is located in a bend of the River Wensum, which formerly enhanced the city's defences. For centuries, the whole region was isolated by marsh and fen. The river was a key trade artery linking Norwich to the sea. Nowadays, Norwich is the gateway to two hundred miles of tranquil lakes and rivers - The Norfolk Broadlands National Park - with a huge range of facilities for tourists and holidaymakers. These include self hire cabinboat cruising, canoeing, sailing, windsurfing, chalets to rent and numerous riverside pubs.

Evening Activities

The Riverside Quarter comprises a vibrant entertainment and leisure area. It has a wide variety of bars and restaurants, 'Time' - the city's largest nightclub, a UCI multiplex cinema - 14 screen, and the 'Hollywood Bowl' - an upmarket 26 lane tenpin bowling centre.

Taverns and Restaurants in Norwich are legion. The City was once said to have a church for every week of the year and a tavern for every day of the year.
A selection of traditional English taverns, within a short semi-circular walk from the west to the northeast side of the Cathedral precinct, includes the 15th century Louis Marchesi (Tombland) with 'crypt' bar, Ha! Ha! (Tombland) the Ribs of Beef (Fyebridge) with a fine range of cask conditioned ales, the Mischief Tavern (Fyebridge), the 16th century Wig and Pen (St Martins Palace Plain) close-by the law courts, and the 13th century haunted Adam and Eve (Bishopgate)
Some popular restaurants include Tatlers (Norfolk cuisine) in Tombland, Trattoria Rustica (Italian) in Princes Street off Tombland, La Tasca (Spanish Tapas) in Tombland, Krasades Taverna (Greek) in Prince of Wales Road, and the Sugar Hut (Thai) in Opie Street.

The City Ghost Walks take place Monday to Thursday evenings starting from the Adam and Eve Pub in Bishopgate. An entertaining two hour journey into the supernatural exploring the City's ghostly and sometimes macabre past.

Floodlit River Cruises take place Wednesday and Friday evenings. Boarding late evening from Station Quay these are of approximately one and a half hours duration.

Market Scene and Tavern

Market Shopping

Royal Shopping Arcade

Cathedral Interior

Norfolk Country Tavern

Broadlands Scene

Scenes from Previous
Years Symposia

EXHIBITION/ EXHIBITOR ENQUIRIES

The Symposium Exhibition will cover all aspects of Automation, Synthesis and Screening, Instrumentation, Reagents and Supplies, etc., will be held in the newly refurbished Hive Exhibition Hall close by the Symposium Lecture Theatres. The Exhibition opens with a Free Evening Welcome Reception on Tuesday 29th August and continues through Wednesday 29th August and Thursday 30th August to the end of the Lunch Break on Friday 31st August, 2007. The Exhibition runs concurrently with the Symposium Lecture Sessions and the associated Scientific Poster Displays. Throughout the Lecture Programme, there will be Extended Tea/Coffee Breaks, up to one hour duration, with service points located exclusively within the Exhibition Area.

Please click here to obtain the Symposium Exhibitor Enquiry Form

Potential Exhibitors completing this form will receive details of Exhibition Stand Display Areas, the Exhibition Floor Plan, Advertising in the Conference Wallet, possibilities for Exhibitor's Commercial Mini-symposia, opportunities for sponsorship, etc.

This Web Page is part of the Mayflower Worldwide Web Site which is updated regularly to provide a gateway to information sources relevant to chemical, biological and biomedical aspects
of peptide, protein and nucleic acid science, bio-organic combinatorial libraries,
drug discovery, development and delivery, etc. Please visit each month !

Web Site designed, created and maintained by Mayflower Worldwide Ltd

The Copyright Owner of each Company Logo displayed on this Web Site is the Company to which it relates. The Copyright Owner of all other Animated Gifs, Artwork, and Photos herein is Mayflower Worldwide Ltd, excepting those items which are displayed by permission of the otherwise Copyright Owner.

Scientific and Technical Contact: Prof Roger Epton,
Mayflower Worldwide Ltd, PO Box 13, West Midlands, Kingswinford, DY6 0HR, England, UK
E-MAIL: r.epton@mayflower.demon.co.uk; TEL/FAX: +44 (0) 1384 279324