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Strategy and Advances in Synthesis
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"New Tricks for Solid
Phase Peptide Synthesis"
- Prof Fernando Albericio (IRBB-PCB,
University of Barcelona, Barcelona, Spain) |
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"Structure-breaking
Dipeptides and Depsipeptides for Expediting the Fmoc SPPS of Complex and
Difficult Peptides"
- Dr Peter White, (Merck Chemicals Ltd.,
Nottingham, NG9 2JR, UK) |
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"A Novel Approach to
the Chemical Synthesis of PNA"
- Dr Ravi Vinayak, Hyunil Lee,
Sung Kee Kim, Jae Hoon Jeon, Jong Chan Lim, Hoon Choi, Yeohong Yoon and Hey
Yeon Kim (PANAGENE INC., 100, Sinsung-dong, Yuseong-gu, Daejeon, 305-345,
Korea) |
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Synthetic Assemblies with Therapeutic &
Drug Potential (I) - Applications, Targeting & Delivery
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"Peptides for Tumour
Targeting"
- Prof Alex Eberle (University Hospital Basel,
Basel, Switzerland) |
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"Cell-Penetrating
Peptides and Applications in Gene Regulation"
- Prof Ulo
Langel (Dept. Neurochemistry, Stockholm University, S-106 91 Stockholm,
Sweden |
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Synthetic Peptide Epitopes for Antibody and Vaccine
Strategies |
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"Functional
Reconstruction of Structurally Complex Epitopes Using CLIPS-Technology"
- Dr Peter Timmerman, W.C Puijk and R.H. Meloen, (Pepscan
Therapeutics B.V., Runderweg 4-6, P.O. Box 2098, Lelystad, The Netherlands)
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"Synthesis and
Application of Peptide Epitope Conjugates for Diagnosis/Therapy of Infectious
Diseases"
- Prof Dr Ferenc
Hudecz [a,b] , Annamária Jakab [a] , Gábor Mezo
[a] , Kata Horváti [a] , Szilvia Bosze [a] , Nadia Caccamo [c] ,
Francesco Dieli [c] , Matty Feijlbrief [d] , Sytske Welling-Wester [d] ,
Dimitrios Krikorian [e] , Vassilios Tsikaris [e] , Miquel Vila Perello [f] and
David Andreu [f] ([a] Research Group of Peptide Chemistry, Hungarian Academy
of Sciences, Eötvös L. University, [b] Department of Organic
Chemistry, Eötvös L. University, 1518 Budapest 112 POB 32, H-1518,
Hungary, [c] Department of Biopathology, University of Palermo, Palermo, Italy,
[d] Laboratory for Medical Microbiology, Rijksuniversiteit Groningen,
Groningen, The Netherlands, [e] Department of Chemistry, University of
Ioannina, Ioannina, Greece, [f] Department of Experimental and Health Sciences,
Pompeu Fabra University, Barcelona, Spain) |
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"Synthetic Mimicry of
the CD4-Binding Site of HIV-1 gp120 for the Design of Immunogens"
Raimo
Franke, Tatjana Hirsch, Heike Overwin and Dr Jutta Eichler (Helmholtz
Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany )
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"Mass Spectrometric
Identification and Immuno-Analytical Characterization of beta-Amyloid Epitopes"
Dr Marilena Manea [1], Raluca Stefanescu [1], Gábor Mezo
[2], Ferenc Hudecz [2] and Michael Przybylski [1] ([1] University of
Konstanz, Department of Chemistry, Laboratory of Analytical Chemistry and
Biopolymer Structure Analysis, Universitaetsstrasse 10, 78457 Konstanz,
Germany, [2] Research Group of Peptide Chemistry, Hungarian Academy of
Sciences, Eötvös L. University, 1518 Budapest 112 POB 32, H-1518,
Hungary) |
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Support Matrix Developments and Techniques
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"A Novel Approach to
Encapsulation of Soft Gel Polymers for Peptide, Oligonucleotide and
Combinatorial Chemistry"
- Dr Donald Wellings (Chromatide
Ltd, Runcorn, Cheshire, UK) |
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" PEG Update: An Old
Fellow in New Applications"
- Dr Wolfgang Rapp (Rapp Polymere
GmbH, Ernst-Simon-Strasse 9, Tuebingen, Germany) |
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"Automated SPS
Workflows"
- Dr Jake Grace [1], Joseph Schroder [2], Jerome
Giovannoni [2], Nhat Quang Nguyen-Trung [2], Peter White [3], Anthony Clouet
[4], Estelle Delort [4], Jean-Louis Reymond [4], Michael Calerini [5], Stefan
Bender [5], Hans-Peter Buchstaller [6] ([1] Chemspeed Technologies,
Northampton, England, UK, [2] Chemspeed Technologies, Augst, Switzerland, [3]
CN Biosciences, Nottingham, England, [4] University of Bern, Bern, Switzerland,
[5] Merck, Darmstadt, Germany) |
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Combinatorial Libraries and Microarrays
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"Advancement and
Application of High-density Chemical Microarrays to Probe for Protein-Drug
Interactions"
Ulrike Beutling, Antonius Dikmans, Edelgard Schmeisser,
Sabine Thiele, and Dr Ronald Frank (Helmholtz Centre for Infection
Research, Inhoffenstr. 7, D-38124, Braunschweig, Germany) |
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"Construction of
Structured Labeled Peptide Libraries for Peptide Arrays Focusing on Protein
Detection Systems"
- Prof Dr Kiyoshi Nokihara [1,2], Takafumi
Ohyama [1], Noriko Ono [1], Hirochika Kawakami [2], Noboru Kawahira [2], Yukiko
Kodama [2], Naeko Miyazato [2], Kanae Suzuki [1], Tetsuya Sogon [1], Akiyoshi
Hirata [1], Midori Miyajima [1], Takayasu Kawasaki [1], Yasushi Takebayashi [3]
and Yasuo Oka [3] ([1] HiPep Laboratories, Kyoto, 602-8158, Japan, [2] HiPep
Laboratories, Okinawa, 904-2234, Japan, [3] Nippon Light Metal Company, Ltd.,
Shizuoka 421-3291, Japan) |
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Synthetic Assemblies with Therapeutic & Drug Potential
(II) - Applications, Targeting & Delivery |
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"Synthesis of Peptide
Conjugates of PNA with High Splicing Redirection Activity and Inhibition of
MicroRNA"
Gabriela D. Ivanova [1], Andrey A. Arzumanov [1], Martin M.
Fabani [1], Saïd Abes [2], Rachida Abes [2], Donna Williams [1], David
Owen [1], Bernard Lebleu [2] and Dr Michael J. Gait [1] ([1] Medical
Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge CB2
0QH UK and [2] UMR 5235 CNRS, Université Montpellier 2, Place Eugene
Bataillon, 34095 Montpellier, cedex 5, France) |
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"Protein and Protein
Conjugate - based Medicines"
- Prof Stephen Brocchini
(Department of Pharmaceutics, School of Pharmacy, 29/39 Brunswick Square,
London, UK) |
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"Inhibiting Proteins
by Shifting their Oligomerization Equilibrium: Application for HIV-1 Integrase"
Zvi Hayouka [1], Joseph Rosenbluh [2], Aviad Levin [2,3], Shoshana Loya
[4], Mario Lebendiker [5], Dmitry Veprintsev [6], Moshe Kotler [3], Amnon Hizi
[4], Abraham Loyter [2] & Dr Assaf Friedler [1] ([1] Department
of Organic Chemistry, [2] Department of Biological Chemistry, The Hebrew
University of Jerusalem, Givat Ram, Jerusalem 91904, Israel; [3] Department of
Pathology, The Hebrew University-Hadassah Medical School, Jerusalem 91120,
Israel; [4] Department of Cell and Developmental Biology, The Sackler School of
Medicine, Tel Aviv University, Tel Aviv 69978, Israel; [5] Protein Purification
Unit, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904,
Israel;[6] Centre for Protein Engineering, MRC Centre, Hills Road, Cambridge
CB2 2QH, UK) |
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Advanced Diagnostic Assemblies
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"Direct Synthesis of
Oligonucleotides on Metallic Nanoparticles and Their Use as Diagnostic
Probes"
- Prof Duncan Graham, Julian Sikorski, David Thompson,
Jennifer Dougan, Karen Faulds and Fiona McKenzie (Centre for Molecular
Nanometrology, Department of Pure and Applied Chemistry, University of
Strathclyde, Glasgow, G1 1XL, Scotland, UK) |
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"Synthesis of
beta-Amyloid-binding Peptides as Contrast Agents for MRI-Diagnosis of
Alzheimer's Disease"
Yeser Mohammad and Prof Brian Austen
(Basic Medical Sciences, St George's University of London. Tooting, London
SW17 ORE, UK) |
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Synthetic Studies of Significance for Drug Development
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"Towards Drug
Development of Insulin-like Peptide3, A Potential New Fertility-regulating
Peptide"
Fazel Shabanpoor [1,2], Suode Zhang [1], Feng Lin [1], R. Tony
Hughes [3], Ross A. Bathgate [1] and Prof John D. Wade [1] ([1]
Howard Florey Institute, [2] School of Chemistry and [3] Department of
Pharmacology, University of Melbourne, Victoria 3010, Australia)
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"Novel Amino Acid
Derivatives and Their Applications in Drug Discovery"
- Dr Ram P.
Sharma and Patrick Kanda (ActivotecSSP Ltd, School of Biological
Sciences, University of Southampton, Bassett Crescent East, Southampton, SO16
7PX, UK) |
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"Solid Phase
Synthesis of Cyclic Peptide Chitinase Inhibitors"
M.J. Dixon [a], A.
Nathubhai [a], O.A. Andersen [b], D.M.F. van Aalten [b] and Dr Ian M.
Eggleston* [a] ( [a] Department of Pharmacy and Pharmacology, University
of Bath, Bath BA2 7AY, UK, [b] School of Life Sciences, University of Dundee,
Dundee DD1 5EH, UK) |
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"The Synthesis of MDa
Polypeptides Using Self-assembled Templates"
- Dr Maxim G.
Ryadnov [1] and Derek N Woolfson [1,2] ([1] School of Chemistry,
University of Bristol, Bristol, BS8 1TS, UK, [ 2] Department of Biochemistry,
School of Medical Sciences, University of Bristol, Bristol, BS8 1TD, UK)
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"Toll-like Receptor
Ligands Synthesized by Combinatorial Lipopeptide Chemistry"
- Prof.
Dr. Karl-Heinz Wiesmueller (EMC Microcollections GmbH,Sindelfinger Str.
3, D-72070 Tuebingen, Germany) |
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